Spondylolisthesis What is spondylolisthesis? Spondylolisthesis is a condition where one of the vertebra slips forwards or backwards onto the vertebra next to it leading to a spinal deformity. What are the symptoms of spondylolisthesis? Symptoms of spondylolisthesis includes pain in the lower back, tightness and discomfort in the hamstrings, tingling, pain, and limited range of motion in the back and legs. How do we treat spondylolisthesis?